Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion

Leukocytes arrested on inflamed endothelium via integrins are subjected to force imparted by flowing blood. How leukocytes respond to this force and resist detachment is poorly understood. Live-cell imaging with Lifeact-transfected U937 cells revealed that force triggers actin polymerization at upst...

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Hlavní autoři: Rullo, Jacob, Becker, Henry, Hyduk, Sharon J., Wong, Janice C., Digby, Genevieve, Arora, Pamma D., Cano, Adrianet Puig, Hartwig, John, McCulloch, Christopher A., Cybulsky, Myron I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317807/
https://ncbi.nlm.nih.gov/pubmed/22472442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107140
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