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Mesenchymal Stem Cells Induce Functionally Active T-Regulatory Lymphocytes in a Paracrine Fashion and Ameliorate Experimental Autoimmune Uveitis
PURPOSE. Mesenchymal stem/progenitor cells (MSCs) have regenerative and immunomodulatory properties, exerted by cell-cell contact and in a paracrine fashion. Part of their immunosuppressive activity has been ascribed to their ability to promote the induction of CD4(+)CD25(+)FoxP3(+) T lymphocytes wi...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association for Research in Vision and Ophthalmology, Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317420/ https://ncbi.nlm.nih.gov/pubmed/22232435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8211 |
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