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Mesenchymal Stem Cells Induce Functionally Active T-Regulatory Lymphocytes in a Paracrine Fashion and Ameliorate Experimental Autoimmune Uveitis

PURPOSE. Mesenchymal stem/progenitor cells (MSCs) have regenerative and immunomodulatory properties, exerted by cell-cell contact and in a paracrine fashion. Part of their immunosuppressive activity has been ascribed to their ability to promote the induction of CD4(+)CD25(+)FoxP3(+) T lymphocytes wi...

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Bibliographische Detailangaben
Hauptverfasser: Tasso, Roberta, Ilengo, Cristina, Quarto, Rodolfo, Cancedda, Ranieri, Caspi, Rachel R., Pennesi, Giuseppina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317420/
https://ncbi.nlm.nih.gov/pubmed/22232435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8211
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