Dietary Omega-3 Polyunsaturated Fatty Acids Suppress NHE-1 Upregulation in a Rabbit Model of Volume- and Pressure-Overload

Background: Increased consumption of omega-3 polyunsaturated fatty acids (ω3-PUFAs) from fish oil (FO) may have cardioprotective effects during ischemia/reperfusion, hypertrophy, and heart failure (HF). The cardiac Na(+)/H(+)-exchanger (NHE-1) is a key mediator for these detrimental cardiac conditio...

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Autors principals: van Borren, Marcel M. G. J., den Ruijter, Hester M., Baartscheer, Antonius, Ravesloot, Jan H., Coronel, Ruben, Verkerk, Arie O.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317268/
https://ncbi.nlm.nih.gov/pubmed/22485092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00076
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