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Evolutionary rate covariation reveals shared functionality and coexpression of genes
Evolutionary rate covariation (ERC) is a phylogenetic signature that reflects the covariation of a pair of proteins over evolutionary time. ERC is typically elevated between interacting proteins and so is a promising signature to characterize molecular and functional interactions across the genome....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317153/ https://ncbi.nlm.nih.gov/pubmed/22287101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.132647.111 |
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