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Evolutionary rate covariation reveals shared functionality and coexpression of genes

Evolutionary rate covariation (ERC) is a phylogenetic signature that reflects the covariation of a pair of proteins over evolutionary time. ERC is typically elevated between interacting proteins and so is a promising signature to characterize molecular and functional interactions across the genome....

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Detalhes bibliográficos
Main Authors: Clark, Nathan L., Alani, Eric, Aquadro, Charles F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317153/
https://ncbi.nlm.nih.gov/pubmed/22287101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.132647.111
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