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Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning

Undernutrition during pregnancy is implicated in the programming of offspring for the development of obesity and diabetes. We hypothesized that maternal programming causes epigenetic changes in fetal hypothalamic pathways regulating metabolism. This study used sheep to examine the effect of moderate...

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書誌詳細
主要な著者: Begum, Ghazala, Stevens, Adam, Smith, Emma Bolton, Connor, Kristin, Challis, John R. G., Bloomfield, Frank, White, Anne
フォーマット: Artigo
言語:Inglês
出版事項: Federation of American Societies for Experimental Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316895/
https://ncbi.nlm.nih.gov/pubmed/22223754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-198762
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