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γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor

Reactive oxygen species regulate redox-signaling processes, but in excess they can cause cell damage, hence underlying the aetiology of several neurological diseases. Through its ability to down modulate reactive oxygen species, glutathione is considered an essential thiol-antioxidant derivative, ye...

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Detalhes bibliográficos
Main Authors: Quintana-Cabrera, Ruben, Fernandez-Fernandez, Seila, Bobo-Jimenez, Veronica, Escobar, Javier, Sastre, Juan, Almeida, Angeles, Bolaños, Juan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316877/
https://ncbi.nlm.nih.gov/pubmed/22395609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1722
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