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Joining Forces: Integrating Proteomics and Cross-linking with the Mass Spectrometry of Intact Complexes

Protein assemblies are critical for cellular function and understanding their physical organization is the key aim of structural biology. However, applying conventional structural biology approaches is challenging for transient, dynamic, or polydisperse assemblies. There is therefore a growing deman...

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Detalles Bibliográficos
Main Authors: Stengel, Florian, Aebersold, Ruedi, Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316738/
https://ncbi.nlm.nih.gov/pubmed/22180098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R111.014027
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