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Joining Forces: Integrating Proteomics and Cross-linking with the Mass Spectrometry of Intact Complexes

Protein assemblies are critical for cellular function and understanding their physical organization is the key aim of structural biology. However, applying conventional structural biology approaches is challenging for transient, dynamic, or polydisperse assemblies. There is therefore a growing deman...

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Autors principals: Stengel, Florian, Aebersold, Ruedi, Robinson, Carol V.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316738/
https://ncbi.nlm.nih.gov/pubmed/22180098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R111.014027
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