System-wide Perturbation Analysis with Nearly Complete Coverage of the Yeast Proteome by Single-shot Ultra HPLC Runs on a Bench Top Orbitrap

Yeast remains an important model for systems biology and for evaluating proteomics strategies. In-depth shotgun proteomics studies have reached nearly comprehensive coverage, and rapid, targeted approaches have been developed for this organism. Recently, we demonstrated that single LC-MS/MS analysis...

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Detalhes bibliográficos
Main Authors: Nagaraj, Nagarjuna, Alexander Kulak, Nils, Cox, Juergen, Neuhauser, Nadin, Mayr, Korbinian, Hoerning, Ole, Vorm, Ole, Mann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Special Issue: Prospects in Space and Time
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316726/
https://ncbi.nlm.nih.gov/pubmed/22021278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013722
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