High-Resolution Genome-Wide Analysis of Irradiated (UV and γ-Rays) Diploid Yeast Cells Reveals a High Frequency of Genomic Loss of Heterozygosity (LOH) Events

In diploid eukaryotes, repair of double-stranded DNA breaks by homologous recombination often leads to loss of heterozygosity (LOH). Most previous studies of mitotic recombination in Saccharomyces cerevisiae have focused on a single chromosome or a single region of one chromosome at which LOH events...

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Библиографические подробности
Главные авторы: St. Charles, Jordan, Hazkani-Covo, Einat, Yin, Yi, Andersen, Sabrina L., Dietrich, Fred S., Greenwell, Patricia W., Malc, Ewa, Mieczkowski, Piotr, Petes, Thomas D.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2012
Предметы:
Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316642/
https://ncbi.nlm.nih.gov/pubmed/22267500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.137927
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