Nicorandil Attenuates Monocrotaline-Induced Vascular Endothelial Damage and Pulmonary Arterial Hypertension

BACKGROUND: An antianginal K(ATP) channel opener nicorandil has various beneficial effects on cardiovascular systems; however, its effects on pulmonary vasculature under pulmonary arterial hypertension (PAH) have not yet been elucidated. Therefore, we attempted to determine whether nicorandil can at...

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Autors principals: Sahara, Makoto, Sata, Masataka, Morita, Toshihiro, Hirata, Yasunobu, Nagai, Ryozo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316574/
https://ncbi.nlm.nih.gov/pubmed/22479390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033367
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