Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

Advancement of biomedical applications of carbonaceous nanomaterials is hampered by their biopersistence and pro-inflammatory action in vivo. Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the...

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Bibliografische gegevens
Hoofdauteurs: Shvedova, Anna A., Kapralov, Alexandr A., Feng, Wei Hong, Kisin, Elena R., Murray, Ashley R., Mercer, Robert R., St. Croix, Claudette M., Lang, Megan A., Watkins, Simon C., Konduru, Nagarjun V., Allen, Brett L., Conroy, Jennifer, Kotchey, Gregg P., Mohamed, Bashir M., Meade, Aidan D., Volkov, Yuri, Star, Alexander, Fadeel, Bengt, Kagan, Valerian E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316527/
https://ncbi.nlm.nih.gov/pubmed/22479306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030923
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