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Payload Drug vs. Nanocarrier Biodegradation by Myeloperoxidase- and Peroxynitrite-Mediated Oxidations: Pharmacokinetic Implications

[Image: see text] With the advancement of nanocarriers for drug delivery into biomedical practice, assessments of drug susceptibility to oxidative degradation by enzymatic mechanisms of inflammatory cells become important. Here, we investigate oxidative degradation of a carbon nanotube-based drug ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanoscale
Hauptverfasser: Seo, Wanji, Kapralov, Alexandr A., Shurin, Galina V., Shurin, Michael R., Kagan, Valerian E., Star, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582775/
https://ncbi.nlm.nih.gov/pubmed/25902750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr00251f
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