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MicroRNA Regulation of SIRT1

SIRT1 is an NAD-dependent deacetylase that regulates stress response pathways. By deacetylating transcription factors and co-factors, SIRT1 modulates metabolism, inflammation, hypoxic responses, circadian rhythms, cell survival, and longevity. Since SIRT1 plays a key role in regulating pathways invo...

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Détails bibliographiques
Auteur principal: Yamakuchi, Munekazu
Format: Artigo
Langue:Inglês
Publié: Frontiers Research Foundation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315824/
https://ncbi.nlm.nih.gov/pubmed/22479251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00068
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