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MicroRNA-22 Regulates Hypoxia Signaling in Colon Cancer Cells

MicroRNAs (MiRNAs) are short, non-coding RNA that regulate a variety of cellular functions by suppressing target protein expression. We hypothesized that a set of microRNA regulate tumor responses to hypoxia by inhibiting components of the hypoxia signaling pathway. We found that miR-22 expression i...

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Autors principals: Yamakuchi, Munekazu, Yagi, Shusuke, Ito, Takashi, Lowenstein, Charles J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100326/
https://ncbi.nlm.nih.gov/pubmed/21629773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020291
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