Amifostine Remediates the Degenerative Effects of Radiation on the Mineralization Capacity of the Murine Mandible

BACKGROUND: Although radiotherapy is a cornerstone in head and neck cancer treatment it causes substantial morbidity to the normal adjoining bone. Our specific aim is to assess the radioprotective effect of Amifostine (AMF) therapy on the mineralization of the mandible using micro-computed tomograph...

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Main Authors: Tchanque-Fossuo, Catherine N., Donneys, Alexis, Deshpande, Sagar S., Nelson, Noah S., Boguslawski, Matt J., Gallagher, K. Kelly, Sarhaddi, Deniz, Poushanchi, Behdod, Goldstein, Steven A., Buchman, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315689/
https://ncbi.nlm.nih.gov/pubmed/22456378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e3182454352
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