Immunotherapy With IL-10 and IFN-γ Producing CD4 Effector Cells Modulate “Natural” And “Inducible” CD4 TReg Cell Subpopulation Levels: Observations In Four Cases Of Patients With Ovarian Cancer

Adoptive T cell therapy for cancer patients optimally requires participation of CD4 T cells. In this phase I/II study, we assessed the therapeutic effects of adoptively transferred IL-10 and IFN-γ-producing CD4 effector cells in patients with recurrent ovarian cancer. Using MUC1 peptide and IL-2 for...

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Main Authors: Dobrzanski, Mark J., Rewers-Felkins, Kathleen A., Samad, Khaliquzzaman A., Quinlin, Imelda S., Phillips, Catherine A., Robinson, William, Dobrzanski, David J., Wright, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315597/
https://ncbi.nlm.nih.gov/pubmed/22083345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1128-x
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