Evaluation of Genetic Mutations Associated with Mycobacterium tuberculosis Resistance to Amikacin, Kanamycin and Capreomycin: A Systematic Review

BACKGROUND: Rapid molecular diagnostics for detecting multidrug-resistant and extensively drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium tuberculosis (Mtb) genes associated with drug resistance. Their accuracy, however, is dependent largely on the strength of th...

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Detalhes bibliográficos
Main Authors: Georghiou, Sophia B., Magana, Marisa, Garfein, Richard S., Catanzaro, Donald G., Catanzaro, Antonino, Rodwell, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315572/
https://ncbi.nlm.nih.gov/pubmed/22479378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033275
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