Compensatory T-Cell Regulation in Unaffected Relatives of SLE Patients, and Opposite IL-2/CD25-Mediated Effects Suggested by Coreferentiality Modeling

In human systemic lupus erythematosus (SLE), diverse autoantibodies accumulate over years before disease manifestation. Unaffected relatives of SLE patients frequently share a sustained production of autoantibodies with indiscriminable specificity, usually without ever acquiring the disease. We stud...

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Detalhes bibliográficos
Main Authors: Fesel, Constantin, Barreto, Marta, Ferreira, Ricardo C., Costa, Nuno, Venda, Lara L., Pereira, Clara, Carvalho, Claudia, Morães-Fontes, Maria Francisca, Ferreira, Carlos M., Vasconcelos, Carlos, Viana, João F., Santos, Eugenia, Martins, Berta, Demengeot, Jocelyne, Vicente, Astrid M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315511/
https://ncbi.nlm.nih.gov/pubmed/22479496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033992
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