Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

BACKGROUND: In addition to cytotoxic mechanisms directly impacting neurons, β-amyloid (Aβ)-induced glial activation also promotes release of proinflammatory molecules that may self-perpetuate reactive gliosis and damage neighbouring neurons, thus amplifying neuropathological lesions occurring in Alz...

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Main Authors: Scuderi, Caterina, Valenza, Marta, Stecca, Claudia, Esposito, Giuseppe, Carratù, Maria Rosaria, Steardo, Luca
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315437/
https://ncbi.nlm.nih.gov/pubmed/22405189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-49
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