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Sequence independent duplex DNA opening reaction catalysed by SV40 large tumor antigen.

Simian virus 40 (SV40) large tumor antigen (T antigen) is mainly localized in the nucleus where it exhibits two biochemical properties: DNA binding and helicase activity. Both activities are necessary for viral DNA replication and may also enable T antigen to modulate cellular growth. Here we presen...

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Detalhes bibliográficos
Main Authors: Scheffner, M, Wessel, R, Stahl, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC331537/
https://ncbi.nlm.nih.gov/pubmed/2536153
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