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A pre-initiation complex at the 3′-end of genes drives antisense transcription independent of divergent sense transcription

The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3′ regions of genes possess a promoter architecture, including a pre-initiation complex (PIC), which mirrors that at the 5′ region and which is much more pronounced at ge...

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Detalhes bibliográficos
Main Authors: Murray, Struan C., Serra Barros, Ana, Brown, David A., Dudek, Peter, Ayling, Jonathan, Mellor, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315312/
https://ncbi.nlm.nih.gov/pubmed/22123739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1121
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