Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the α(M)β(2) leukocyte integrin receptor

In Duchenne muscular dystrophy (DMD), a persistently altered and reorganizing extracellular matrix (ECM) within inflamed muscle promotes damage and dysfunction. However, the molecular determinants of the ECM that mediate inflammatory changes and faulty tissue reorganization remain poorly defined. He...

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Main Authors: Vidal, Berta, Ardite, Esther, Suelves, Mònica, Ruiz-Bonilla, Vanessa, Janué, Anna, Flick, Matthew J., Degen, Jay L., Serrano, Antonio L., Muñoz-Cánoves, Pura
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315206/
https://ncbi.nlm.nih.gov/pubmed/22381526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds012
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