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BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes
There are numerous genes for which loss-of-function mutations do not produce apparent phenotypes even though statistically significant quantitative changes to biological pathways are observed. To evaluate the biological meaning of small effects is challenging. Bardet–Biedl syndrome (BBS) is a hetero...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315203/ https://ncbi.nlm.nih.gov/pubmed/22228099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds004 |
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