BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

There are numerous genes for which loss-of-function mutations do not produce apparent phenotypes even though statistically significant quantitative changes to biological pathways are observed. To evaluate the biological meaning of small effects is challenging. Bardet–Biedl syndrome (BBS) is a hetero...

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Bibliographic Details
Main Authors: Zhang, Qihong, Seo, Seongjin, Bugge, Kevin, Stone, Edwin M., Sheffield, Val C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315203/
https://ncbi.nlm.nih.gov/pubmed/22228099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds004
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