Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signalling pathway in human umbilical vein endothelial cells

BACKGROUND AND PURPOSE: One key mechanism for endothelial dysfunction is endothelial NOS (eNOS) uncoupling, whereby eNOS generates superoxide (O(2)(•−)) rather than NO. We explored the effect of pyridoxine on eNOS uncoupling induced by oxidized low-density lipoprotein (ox-LDL) in human umbilical vei...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Xie, Liping, Liu, Zhen, Lu, Hui, Zhang, Wen, Mi, Qiongyu, Li, Xiaozhen, Tang, Yan, Chen, Qi, Ferro, Albert, Ji, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315046/
https://ncbi.nlm.nih.gov/pubmed/21797845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01607.x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky