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DNA polymerase ɛ is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts

DNA polymerase ɛ (Polɛ) is thought to be involved in DNA replication, repair, and cell-cycle checkpoint control in eukaryotic cells. Although the requirement of other replicative DNA polymerases, DNA polymerases α and δ (Polα and δ), for chromosomal DNA replication has been well documented by geneti...

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Main Authors: Waga, Shou, Masuda, Taro, Takisawa, Haruhiko, Sugino, Akio
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC33149/
https://ncbi.nlm.nih.gov/pubmed/11296256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081088798
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