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Xenopus Cdc6 Performs Separate Functions in Initiating DNA Replication

Cdc6 performs an essential role in the initiation of eukaryotic DNA replication by recruiting the minichromosome maintenance (MCM) complex onto DNA. Using immunodepletion/add-back experiments in Xenopus egg extracts, we have determined that both Walker A (ATP binding) and Walker B (ATP hydrolysis) m...

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Detalhes bibliográficos
Main Authors: Frolova, Natalya S., Schek, Nancy, Tikhmyanova, Nadia, Coleman, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102270/
https://ncbi.nlm.nih.gov/pubmed/11950940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-08-0382
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