Xenopus Cdc6 Performs Separate Functions in Initiating DNA Replication

Cdc6 performs an essential role in the initiation of eukaryotic DNA replication by recruiting the minichromosome maintenance (MCM) complex onto DNA. Using immunodepletion/add-back experiments in Xenopus egg extracts, we have determined that both Walker A (ATP binding) and Walker B (ATP hydrolysis) m...

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Bibliographic Details

Published in:	Mol Biol Cell
Main Authors:	Frolova, Natalya S., Schek, Nancy, Tikhmyanova, Nadia, Coleman, Thomas R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Cell Biology 2002
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11950940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-08-0382
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