Ocular Application of the Kinin B(1) Receptor Antagonist LF22-0542 Inhibits Retinal Inflammation and Oxidative Stress in Streptozotocin-Diabetic Rats

PURPOSE: Kinin B(1) receptor (B(1)R) is upregulated in retina of Streptozotocin (STZ)-diabetic rats and contributes to vasodilation of retinal microvessels and breakdown of the blood-retinal barrier. Systemic treatment with B(1)R antagonists reversed the increased retinal plasma extravasation in STZ...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Pouliot, Mylène, Talbot, Sébastien, Sénécal, Jacques, Dotigny, Florence, Vaucher, Elvire, Couture, Réjean
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314679/
https://ncbi.nlm.nih.gov/pubmed/22470485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033864
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi