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Fusion of the Mycobacterium tuberculosis Antigen 85A to an Oligomerization Domain Enhances Its Immunogenicity in Both Mice and Non-Human Primates
To prevent important infectious diseases such as tuberculosis, malaria and HIV, vaccines inducing greater T cell responses are required. In this study, we investigated whether fusion of the M. tuberculosis antigen 85A to recently described adjuvant IMX313, a hybrid avian C4bp oligomerization domain,...
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Główni autorzy: | , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2012
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314664/ https://ncbi.nlm.nih.gov/pubmed/22470455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033555 |
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