Human Embryonic Stem Cells Differentiated to Lung Lineage-Specific Cells Ameliorate Pulmonary Fibrosis in a Xenograft Transplant Mouse Model

BACKGROUND: Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategies to repair lung injury in the bleomy...

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Detalhes bibliográficos
Main Authors: Banerjee, Ena Ray, Laflamme, Michael A., Papayannopoulou, Thalia, Kahn, Michael, Murry, Charles E., Henderson, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314647/
https://ncbi.nlm.nih.gov/pubmed/22470441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033165
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