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Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of non-apoptotic cell death
Methuosis is a novel caspase-independent form of cell death in which massive accumulation of vacuoles derived from macropinosomes ultimately causes cells to detach from the substratum and rupture. We recently described a chalcone-like compound, 3-(2-methyl-1H indol-3-yl)-1-(4-pyridinyl)-2-propen-1-o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314534/ https://ncbi.nlm.nih.gov/pubmed/22335538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201006x |
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