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Parkinson’s disease: don’t mess with calcium

The hallmark of the movement disorder Parkinson’s disease (PD) is progressive degeneration of dopaminergic neurons. Mitochondrial dysfunction, impaired ubiquitin-mediated proteolysis of α-synuclein, and ER stress are each implicated in the complex and poorly understood sequence of events leading to...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Mattson, Mark P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314478/
https://ncbi.nlm.nih.gov/pubmed/22446181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62835
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