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Parkinson’s disease: don’t mess with calcium
The hallmark of the movement disorder Parkinson’s disease (PD) is progressive degeneration of dopaminergic neurons. Mitochondrial dysfunction, impaired ubiquitin-mediated proteolysis of α-synuclein, and ER stress are each implicated in the complex and poorly understood sequence of events leading to...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314478/ https://ncbi.nlm.nih.gov/pubmed/22446181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62835 |
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