β(1) Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

Integrin signaling critically contributes to the progression, growth, and therapy resistance of malignant tumors. Here, we show that targeting of β(1) integrins with inhibitory antibodies enhances the sensitivity to ionizing radiation and delays the growth of human head and neck squamous cell carcin...

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Detaylı Bibliyografya
Asıl Yazarlar: Eke, Iris, Deuse, Yvonne, Hehlgans, Stephanie, Gurtner, Kristin, Krause, Mechthild, Baumann, Michael, Shevchenko, Anna, Sandfort, Veit, Cordes, Nils
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314473/
https://ncbi.nlm.nih.gov/pubmed/22378044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61350
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