Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Recent studies reveal a strong relationship between reduced mitochondrial content and insulin resistance in human skeletal muscle, although the underlying factors responsible for this association remain unknown. To address this question, we analyzed muscle biopsy samples from young, lean, insulin re...

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Detalhes bibliográficos
Main Authors: Morino, Katsutaro, Petersen, Kitt Falk, Sono, Saki, Choi, Cheol Soo, Samuel, Varman T., Lin, Aiping, Gallo, Amy, Zhao, Hongyu, Kashiwagi, Atsunori, Goldberg, Ira J., Wang, Hong, Eckel, Robert H., Maegawa, Hiroshi, Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314372/
https://ncbi.nlm.nih.gov/pubmed/22368174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1391
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