Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Recent studies reveal a strong relationship between reduced mitochondrial content and insulin resistance in human skeletal muscle, although the underlying factors responsible for this association remain unknown. To address this question, we analyzed muscle biopsy samples from young, lean, insulin re...

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Bibliografische gegevens
Hoofdauteurs: Morino, Katsutaro, Petersen, Kitt Falk, Sono, Saki, Choi, Cheol Soo, Samuel, Varman T., Lin, Aiping, Gallo, Amy, Zhao, Hongyu, Kashiwagi, Atsunori, Goldberg, Ira J., Wang, Hong, Eckel, Robert H., Maegawa, Hiroshi, Shulman, Gerald I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2012
Onderwerpen:
Pathophysiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314372/
https://ncbi.nlm.nih.gov/pubmed/22368174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1391
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