A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products

BACKGROUND: The optimal enzyme blend which maximizes human islets yield for transplantation remains to be determined. In this study, we evaluated 8 different enzyme combinations (ECs) in an attempt to improve islet yield. The ECs consisted of purified, intact, or truncated class 1 (C1) and class 2 (...

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Hauptverfasser: Balamurugan, A.N., Loganathan, Gopalakrishnan, Bellin, Mellina, D., Wilhelm, Joshua J., Harmon, James, Anazawa, Takayuki, Soltani, Sajjad M., Radosevich, David M., Yuasa, Takeshi, Tiwari, Mukesh, Papas, Klearchos K., McCarthy, Robert, Sutherland, David E.R., Hering, Bernhard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314155/
https://ncbi.nlm.nih.gov/pubmed/22318245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318247281b
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