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Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin

Many antidepressant drugs, including the tricyclic antidepressant desipramine (DMI), are broadly understood to function by modulating central noradrenergic neurotransmission. α(2) adrenergic receptors (α(2)ARs) are key regulators of the noradrenergic system, and previous work has implicated α(2)ARs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cottingham, Christopher, Li, Xiaohua, Wang, Qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314098/
https://ncbi.nlm.nih.gov/pubmed/22369787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.02.011
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