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Metal binding kinetics of bi-Histidine sites used in ψ-analysis: Evidence for high energy protein folding intermediates

The zinc-specific fluorophore, Zinpyr-1, is used in competition assays to determine the kinetic and thermodynamic parameters of Zn(2+) binding to engineered bi-Histidine sites located in Ubiquitin and the B domain of protein A (BdpA). These binding sites are used in ψ-analysis studies to investigate...

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Detalhes bibliográficos
Main Authors: Bosco, Gerra L., Baxa, Michael, Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313835/
https://ncbi.nlm.nih.gov/pubmed/19220047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802072u
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