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Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice
Limb anomalies are important birth defects that are incompletely understood genetically and mechanistically. GLI3, a mediator of hedgehog signaling, is a genetic cause of limb malformations including pre- and postaxial polydactyly, Pallister–Hall syndrome and Greig cephalopolysyndactyly. A closely r...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313802/ https://ncbi.nlm.nih.gov/pubmed/22234993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds002 |
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