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Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and Cupferron()
Mandelate racemase (MR, EC 5.1.2.2) from Pseudomonas putida catalyzes the Mg(2+)-dependent interconversion of the enantiomers of mandelate, stabilizing the altered substrate in the transition state by 26 kcal/mol relative to the substrate in the ground state. To understand the origins of this bindin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313677/ https://ncbi.nlm.nih.gov/pubmed/22264153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2018514 |
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