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Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and Cupferron()

Mandelate racemase (MR, EC 5.1.2.2) from Pseudomonas putida catalyzes the Mg(2+)-dependent interconversion of the enantiomers of mandelate, stabilizing the altered substrate in the transition state by 26 kcal/mol relative to the substrate in the ground state. To understand the origins of this bindin...

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Autori principali: Lietzan, Adam D., Nagar, Mitesh, Pellmann, Elise A., Bourque, Jennifer R., Bearne, Stephen L., St Maurice, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313677/
https://ncbi.nlm.nih.gov/pubmed/22264153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2018514
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