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Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo()
A series of dithiocarbamates was prepared by reaction of primary/secondary amines with carbon disulfide in the presence of bases. These compounds were tested for the inhibition of 4 human (h) isoforms of the zinc enzyme carbonic anhydrase, CA (EC 4.2.1.1), hCA I, II, IX and XII, involved in patholog...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313672/ https://ncbi.nlm.nih.gov/pubmed/22276570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300031j |
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