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The influence of scaffold elasticity on germ layer specification of human embryonic stem cells

Mechanical forces are critical to embryogenesis, specifically, in the lineage-specification gastrulation phase, whereupon the embryo is transformed from a simple spherical ball of cells to a multi-layered organism, containing properly organized endoderm, mesoderm, and ectoderm germ layers. Several r...

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Bibliographic Details
Main Authors: Zoldan, Janet, Karagiannis, Emmanouil D., Lee, Christopher Y., Anderson, Daniel G., Langer, Robert, Levenberg, Shulamit
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313669/
https://ncbi.nlm.nih.gov/pubmed/21963156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.09.012
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