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Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into blastocysts, contribute to all tissues of the embryo and integrate into the normal morphogenetic processes, i.e. they are pluripotent. However, a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: van den Brink, Susanne C., Baillie-Johnson, Peter, Balayo, Tina, Hadjantonakis, Anna-Katerina, Nowotschin, Sonja, Turner, David A., Martinez Arias, Alfonso
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302915/
https://ncbi.nlm.nih.gov/pubmed/25371360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113001
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