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Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into blastocysts, contribute to all tissues of the embryo and integrate into the normal morphogenetic processes, i.e. they are pluripotent. However, a...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: van den Brink, Susanne C., Baillie-Johnson, Peter, Balayo, Tina, Hadjantonakis, Anna-Katerina, Nowotschin, Sonja, Turner, David A., Martinez Arias, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302915/
https://ncbi.nlm.nih.gov/pubmed/25371360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113001
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