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Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into blastocysts, contribute to all tissues of the embryo and integrate into the normal morphogenetic processes, i.e. they are pluripotent. However, a...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: van den Brink, Susanne C., Baillie-Johnson, Peter, Balayo, Tina, Hadjantonakis, Anna-Katerina, Nowotschin, Sonja, Turner, David A., Martinez Arias, Alfonso
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302915/
https://ncbi.nlm.nih.gov/pubmed/25371360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113001
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