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Specific Inhibition of the transcription factor Ci by a Cobalt(III)-Schiff base-DNA conjugate
We describe the use of Co(III) Schiff base-DNA conjugates, a versatile class of research tools that target C2H2 transcription factors, to inhibit the Hedgehog (Hh) pathway. In developing mammalian embryos, Hh signaling is critical for the formation and development of many tissues and organs. Inappro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313626/ https://ncbi.nlm.nih.gov/pubmed/22214326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2005577 |
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