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Acute Myeloid Leukemia Targeting by Myxoma Virus In Vivo Depends on Cell Binding But Not Permissiveness to Infection In Vitro

Some oncolytic viruses, such as myxoma virus (MYXV), can selectively target malignant hematopoietic cells, while sparing normal hematopoietic cells. This capacity for discrimination creates an opportunity to use oncolytic viruses as ex vivo purging agents of autologous hematopoietic cell grafts in p...

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Hlavní autoři: Madlambayan, Gerard J., Bartee, Eric, Kim, Manbok, Rahman, Masmudur M., Meacham, Amy, Scott, Edward W., McFadden, Grant, Cogle, Christopher R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312971/
https://ncbi.nlm.nih.gov/pubmed/22341701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2012.01.020
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