Acute Myeloid Leukemia Targeting by Myxoma Virus In Vivo Depends on Cell Binding But Not Permissiveness to Infection In Vitro

Some oncolytic viruses, such as myxoma virus (MYXV), can selectively target malignant hematopoietic cells, while sparing normal hematopoietic cells. This capacity for discrimination creates an opportunity to use oncolytic viruses as ex vivo purging agents of autologous hematopoietic cell grafts in p...

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Detalhes bibliográficos
Main Authors: Madlambayan, Gerard J., Bartee, Eric, Kim, Manbok, Rahman, Masmudur M., Meacham, Amy, Scott, Edward W., McFadden, Grant, Cogle, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312971/
https://ncbi.nlm.nih.gov/pubmed/22341701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2012.01.020
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