Optimizing illumina next-generation sequencing library preparation for extremely at-biased genomes

BACKGROUND: Massively parallel sequencing technology is revolutionizing approaches to genomic and genetic research. Since its advent, the scale and efficiency of Next-Generation Sequencing (NGS) has rapidly improved. In spite of this success, sequencing genomes or genomic regions with extremely bias...

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Main Authors: Oyola, Samuel O, Otto, Thomas D, Gu, Yong, Maslen, Gareth, Manske, Magnus, Campino, Susana, Turner, Daniel J, MacInnis, Bronwyn, Kwiatkowski, Dominic P, Swerdlow, Harold P, Quail, Michael A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312816/
https://ncbi.nlm.nih.gov/pubmed/22214261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-1
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